Today, work from the Trappmann Lab investigating the role of matrix adhesion and degradability was published in Nature Communications. A link to the article is here. The work highlights the power of integrating synthetic hydrogels and microfluidics to define biological mechanisms, and represents a step toward the rational design of tissue engineered vasculature.
Citation:
Liu, J., Long, H., Zeuschner, D., Rader, A.F.B., Polacheck, W.J., Kessler, H., Sorokin, L., Trappmann, B. (2021) “Synthetic extracellular matrices with tailored adhesiveness and degradability support lumen formation during angiogenic sprouting.” Nature Communications. 12, 3402.